The team takes on the case of Derrick (guest star Skylar Astin), a 19-year-old college student who had a mysterious nose bleed during cheerleading practice, and discovers that his health issues are likely both physiological and psychological. Possibly suffering from schizophrenia, Derrick claims to hear his deceased brother’s voice in his head.

Meanwhile, Wilson gets advice from former colleague Thirteen (guest star Wilde) and Foreman tries a different approach with House in the all-new “Holding On” episode of HOUSE airing Monday, May 14 (9:00-10:00 PM) on FOX 50. (HOU-821) (TV-14, D, L, V)

Cast: Hugh Laurie as Dr. Gregory House; Robert Sean Leonard as Dr. James Wilson; Omar Epps as Dr. Eric Foreman; Jesse Spencer as Dr. Robert Chase; Peter Jacobson as Dr. Chris Taub; Odette Annable as Dr. Jessica Adams; Charlyne Yi as Dr. Chi Park

Guest Cast: Skylar Astin as Derrick; Olivia Wilde as Thirteen; Moira Squier as Jen; Natalie Dreyfuss as Courtney; Derek Mio as Floyd; Enzo Cilenti as Matt Johnson; Joshua Rush as Ryan; Jacob Zachar as Mikey; David Wells as Milton; Lyn Alicia Henderson as Vet; David Waknine as Janitor; David Fraioli as Janitor #2; Pat McNeely as Woman; Michael C. Alexander as Man; Brayden Brooks as 6 yr. old Christopher; Bobbin Bergstrom as Nurse